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Drug Safety Considerations, Part 2: Drug Distribution

How and where a medication is distributed throughout the body has implications on its prospect of effectiveness and likeliness of adverse effects or toxicities.  A pharmacology expert can evaluate and opine with reasonable pharmaceutical certainty the association between drug exposure and outcome, including the relevance of Read More …

Drug Safety Considerations, Part 1: Absorption

Pharmacokinetics, the science of how a drug becomes available for activity in the body, encompasses four primary variables: Absorption, Distribution, Metabolism and Elimination.  Each of these is impacted by individual variation and impactful to the ultimate clinical and/or adverse effect of a drug. Absorption generally Read More …